Psychology Paradigm Challenge

Depressed people often work harder to avoid threats instead of giving up.

April 20, 2026

Original Paper

Beyond passivity: Depressive symptoms predict persistent active avoidance under ambiguity

Ryan J. Tomm, Liz Kalenteridis, Amanda C. Lee, Ashton Thorpe, Evan White, Luke Clark, Stan B. Floresco, Trisha Chakrabarty, Rebecca M. Todd

PsyArXiv · pqzfh_v3

The Takeaway

Clinical models often assume that depression leads to a total loss of motivation and general passivity. Experiments using ambiguous cues show that people with depressive symptoms actually perform more active avoidance tasks than healthy controls. These individuals exert extra effort to escape perceived danger rather than retreating into a shell. This suggests that the perceived lack of drive in depression might actually be a hyper-focus on preventing bad things from happening. Treatment strategies might need to pivot from just encouraging activity to addressing this exhausting cycle of defensive work.

From the abstract

Avoidance behaviors can involve either initiating or suppressing actions to prevent harm. While avoidance generalization has been extensively studied in anxiety, its expression in depression remains poorly understood—particularly when active and inhibitory strategies compete under conditions of ambiguity without corrective feedback. To test whether depressive symptoms are associated with behavioral passivity or persistent strategy expression, we developed a novel instrumental avoidance generaliz