AI & ML Efficiency Breakthrough

Recovers hidden ODE parameters from sparse data with a 487x speedup over gradient-based methods.

March 13, 2026

Original Paper

Inverse Neural Operator for ODE Parameter Optimization

Zhi-Song Liu, Wenqing Peng, Helmi Toropainen, Ammar Kheder, Andreas Rupp, Holger Froning, Xiaojie Lin, Michael Boy

arXiv · 2603.11854

The Takeaway

The Inverse Neural Operator (INO) bypasses Jacobian instabilities in stiff regimes by using a drifting model in parameter space. This allows for near-instantaneous (0.2s) system identification in complex fields like atmospheric chemistry and gene regulation.

From the abstract

We propose the Inverse Neural Operator (INO), a two-stage framework for recovering hidden ODE parameters from sparse, partial observations. In Stage 1, a Conditional Fourier Neural Operator (C-FNO) with cross-attention learns a differentiable surrogate that reconstructs full ODE trajectories from arbitrary sparse inputs, suppressing high-frequency artifacts via spectral regularization. In Stage 2, an Amortized Drifting Model (ADM) learns a kernel-weighted velocity field in parameter space, trans