Life Science First Ever

Dolphins are basically superheroes; they can heal deep cuts perfectly without leaving a single scar.

March 20, 2026

Original Paper

De Novo Regeneration of Rete Ridges during Cetacean skin wound healing

bioRxiv · 10.64898/2026.03.16.711258

The Takeaway

While humans only show this level of complex tissue regeneration in the womb, dolphins can rebuild elaborate skin architectures from scratch even in high-stress, saltwater environments. This discovery challenges the assumption that 'tight-skinned' mammals are inherently poor at regeneration.

From the abstract

Humans are tight-skinned mammals who typically fail to regenerate large full-thickness skin wounds, instead healing with substantial scarring and concomitant loss of function. Mechanical context is a major determinant of this outcome: elevated tissue tension or stiffness promotes fibrotic repair associated with hypertrophic or keloid scarring. Accordingly, regenerative medicine research has relied on diverse animal models to understand scar development and skin regeneration. Loose-skinned mammal