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Nature Is Weird  /  Neuroscience

Abdominal muscle contractions physically squeeze the veins inside your skull to regulate how blood flows through your brain.

Abdominal pressure creates a mechanical coupling that causes ultrafast constrictions in the brain's venous drainage system. Scientists previously thought that blood flow in the skull was managed almost entirely by local neural signals and the heart. These experiments show that the gut and the central nervous system are physically linked through a high-speed pressure circuit. A simple muscle contraction in the torso can immediately change how blood exits the head. This discovery suggests that simple physical movements might be a way to manage brain pressure during trauma or stroke. It reveals a surprising mechanical link between the middle of the body and the top of the head.

Original Paper

Ultrafast venous and sagittal sinus constrictions in the brain driven by abdominal pressure

Zhang, Q.; Garborg, C. S.; Frank, N.; Salehi Shahrbarbaki, F.; Turner, K.; Drew, P. J.

bioRxiv  ·  10.64898/2026.05.02.722426

Nearly all the blood supplying the cortex exits via the bridging veins (BVs) that drain into the superior sagittal sinus (SSS), making these vessels key chokepoints for cerebral blood flow. Using optical imaging in head-fixed mice, we found that the SSS and BVs exhibit ultrafast contractions (<0.1 s) at the onset of locomotion, following whisker stimulation, and upon awakening from sleep. Contractions of the BV and SSS were strongly correlated with abdominal muscle EMG activity and were tightly